Tag Archives: cell

Neutrons paint atomic portrait of prototypical cell signaling enzyme

Illustration of the intricate organization of the PKA structure, wherein different parts of the protein are connected through elaborate hydrogen bonding networks (dashed yellow lines), glued together by the hydrophobic assemblies (light blue and orange volumes) — all working together to build the functional active site. Insert shows protonation of …

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Researchers make important cell division discovery

Credit: CC0 Public Domain Researchers at the University of Dundee have provided important new insights into the regulation of cell division, which may ultimately lead to a better understanding of cancer progression. Cell division, also known as mitosis, is the process by which a parent cell divides into two daughter …

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New cell subtypes classified in mouse brain

Pictured is an axo-axonic cell (AAC) found in the cortex of a mouse brain. Huang and his colleagues discovered that there are multiple subtypes of AACs. Each is distinguished by the arrangement of important connections the chandelier-shaped cells form with neighboring neurons. Credit: Wang et al. Cell Reports 2019 It’s …

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Speedy ‘slingshot’ cell movement observed for the first time

Credit: CC0 Public Domain By slingshotting themselves forward, human cells can travel more than five times faster than previously documented. University of Michigan researchers observed the movement in bioengineered 3-D scaffolds that model stromal tissue—the connective tissue that surrounds organs. The researchers say this method of cell movement, observed …

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Cell isolation research yields promising results

John Oakey, right, and Andrew Hansen study cells in a lab in the University of Wyoming Engineering Building. Credit: UW Photo John Oakey’s work at the cellular and molecular level could radically change the way cancer is treated. Oakey, an associate professor of chemical engineering at the University of Wyoming’s …

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Diabetes impairs multipotent stromal cell antibacterial activity

Credit: Mary Ann Liebert, Inc., publishers A new study reveals that the multipotent stromal cells (MSCs) of persons with diabetes have diminished capacity to fight off bacterial infection, providing new understanding into the basis of diabetes-associated immune dysfunction. The research is published in Stem Cells and Development. Zijun Zhang and …

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Cell editors correct genetic errors

Volker Knoop, Elena Lesch, Bastian Oldenkott, Yingying Yang and Mareike Schallenberg-Rüdinger are investigating a gene correction mechanism in plants known as RNA editing. During this process, one of the RNA building blocks (cytidine, abbreviated C) is chemically converted into another (uridine, abbreviated U). Credit: © Simon Zumkeller/Uni Bonn Almost all …

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Semi-flexible model-based analysis of cell adhesion to hydrogels

Schematic representation of methods for characterizing the physical properties of hydrogel: the bulk stiffness of hydrogel and chain flexibility in viscoelastic networks through the semi-flexible model. Credit: Scientific Reports, doi: https://doi.org/10.1038/s41598-019-38951-7 Hydrogels are commonly used as biomaterials for applications in biomedicine due to their biocompatibility. However, the relationship between biological …

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